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South America Cruises

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South America Cruises

South America cruises encompass a wide range of ocean and river itineraries across an entire continent, with the Amazon Basin representing just one specialized region. Coastal cruises sail along the Atlantic and Pacific shores, connecting major ports such as Buenos Aires, Rio de Janeiro, Valparaíso, and Lima, while also reaching Patagonia, Cape Horn, and the Chilean fjords. Expedition cruising in the Galápagos Islands offers a very different experience focused on wildlife and conservation, while river cruises elsewhere, including Colombia’s Magdalena River, highlight cultural heritage and regional life. Together, South America cruises offer geographic diversity, combining iconic cities, dramatic coastlines, and inland waterways with distinct travel experiences.

South America Cruises Sailing Calendar

Month Number of Itineraries Number of Cruises From Price
Sep 2026 4 4 $5,241 pp
Oct 2026 23 53 $3,000 pp
Nov 2026 51 98 $83 pp
Dec 2026 73 126 $70 pp
Jan 2027 68 138 $569 pp
Feb 2027 65 124 $559 pp
Mar 2027 90 133 $79 pp
Apr 2027 33 58 $79 pp
May 2027 20 64 $3,299 pp
Jun 2027 21 45 $3,299 pp
Jul 2027 11 28 $7,675 pp
Aug 2027 17 34 $3,699 pp
Sep 2027 19 64 $3,549 pp
Oct 2027 37 90 $3,549 pp
Nov 2027 49 91 $353 pp
Dec 2027 65 116 $353 pp
Jan 2028 72 111 $519 pp
Feb 2028 49 86 $409 pp
Mar 2028 47 66 $439 pp
Apr 2028 13 23 $465 pp
May 2028 9 17 $3,639 pp
Jun 2028 8 8 $3,639 pp
Jul 2028 7 7 $3,639 pp
Aug 2028 10 13 $3,739 pp
Sep 2028 5 14 $3,839 pp
Oct 2028 17 33 $4,089 pp
Nov 2028 21 31 $1,280 pp
Dec 2028 10 20 $1,752 pp
Jan 2029 11 14 $1,693 pp
Feb 2029 10 12 $2,382 pp
Mar 2029 4 5 $9,999 pp
Apr 2029 2 2 $11,999 pp
Oct 2029 3 4 $9,999 pp

Cruise Lines Sailing to South America

The cruise lines sail to this destination, spanning a variety of cruise line categories and ship sizes. For each cruise line, you’ll find the number of unique itineraries and sailing dates available.  Signature Preferred Partners may offer added value, exclusive perks, or additional savings.

Signature Collection

Cruise Lines with the SC icon are part of the Signature Collection and often include added value, exclusive perks or additional savings. 

AMA Waterways cruises to South America
AMA Waterways
River Cruise Line
Small River Ships • 60 - 165 guests
19 Itineraries • 395 Cruises
from $3,299
Signature Collection
Aqua Expeditions cruises to South America
Aqua Expeditions
Expedition Cruise Line
Very Small Ships • 16 - 40 guests
9 Itineraries • 329 Cruises
Please Call
Signature Collection
Atlas Ocean Voyages cruises to South America
Atlas Ocean Voyages
Premium / Expedition
Very Small Ships • Up to 200 guests
2 Itineraries • 2 Cruises
from $16,264
Aurora Expeditions cruises to South America
Aurora Expeditions
Expedition Cruise Line
Very Small Ships • Up to 150 guests
3 Itineraries • 4 Cruises
from $16,571
Avalon Waterways cruises to South America
Avalon Waterways
River Cruise Line
Small River Ships • 36 - 165 guests
8 Itineraries • 82 Cruises
from $7,575
Signature Collection
Azamara Cruises cruises to South America
Azamara Cruises
Upper Premium
Small Ships • Up to 700 guests
10 Itineraries • 10 Cruises
from $3,529
Signature Collection
Carnival Cruises cruises to South America
Carnival Cruises
Contemporary Cruise Line
Very Large Ships • Up to 5,200 guests
2 Itineraries • 2 Cruises
from $1,284
Signature Collection
Celebrity Cruises cruises to South America
Celebrity Cruises
Premium Cruise Line
Large Ships • Up to 3,200 guests
11 Itineraries • 25 Cruises
from $1,280
Signature Collection
Costa Cruises cruises to South America
Costa Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,500 guests
50 Itineraries • 112 Cruises
from $445
Crystal Cruises cruises to South America
Crystal Cruises
Luxury Cruise Line
Small Ships • Up to 740 guests
19 Itineraries • 19 Cruises
from $4,300
Signature Collection
Explora Journeys cruises to South America
Explora Journeys
Luxury Cruise Line
Small Ships • Up to 920 guests
11 Itineraries • 13 Cruises
from $4,285
Signature Collection
Holland America Line cruises to South America
Holland America Line
Premium Cruise Line
Mid-Size to Large • Up to 2,600 guests
10 Itineraries • 12 Cruises
from $1,924
Signature Collection
HX Expeditions cruises to South America
HX Expeditions
Expedition Cruise Line
Very Small to Small • 90 - 530 guests
2 Itineraries • 2 Cruises
from $6,440
Signature Collection
Lindblad Expeditions cruises to South America
Lindblad Expeditions
Expedition Cruise Line
Very Small Ships • 28 - 120 guests
6 Itineraries • 6 Cruises
from $12,130
Signature Collection
MSC Cruises cruises to South America
MSC Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,700 guests
114 Itineraries • 394 Cruises
from $70
Norwegian Cruise Line cruises to South America
Norwegian Cruise Line
Contemporary Cruise Line
Large Ships • Up to 4,000 guests
6 Itineraries • 12 Cruises
from $3,139
Signature Collection
Oceania Cruises cruises to South America
Oceania Cruises
Luxury, Adults Only
Small - Mid-Size • 700 - 1,250 guests
16 Itineraries • 16 Cruises
from $4,399
Signature Collection
Ponant Cruises cruises to South America
Ponant Cruises
Upper Premium
Very Small to Small • 32 - 264 guests
3 Itineraries • 4 Cruises
from $4,600
Signature Collection
Princess Cruises cruises to South America
Princess Cruises
Premium Cruise Line
Mid-Size to Large • up to 4,300 guests
9 Itineraries • 12 Cruises
from $1,669
Signature Collection
Regent Seven Seas Cruises cruises to South America
Regent Seven Seas Cruises
Luxury Cruise Line
Small Ships • 490 – 750 guests
13 Itineraries • 13 Cruises
from $6,599
Signature Collection
Scenic Cruises cruises to South America
Scenic Cruises
Rivers & Yacht Cruises
Very Small Ships • 68 - 169 guests
24 Itineraries • 25 Cruises
from $4,704
Seabourn Cruises cruises to South America
Seabourn Cruises
Luxury & Expedition Cruises
Small Ships • 264 – 600 guests
44 Itineraries • 96 Cruises
from $6,433
Signature Collection
Silversea Cruises cruises to South America
Silversea Cruises
Luxury & Expedition Cruises
Small & Mid-Size • 100 – 728 guests
17 Itineraries • 17 Cruises
from $8,000
Signature Collection
Swan Hellenic Cruises cruises to South America
Swan Hellenic Cruises
Expedition Cruise Line
Very Small Ships • 152 – 192 guests
3 Itineraries • 4 Cruises
from $3,000
Tauck River Cruises cruises to South America
Tauck River Cruises
River Cruise Line
Small River Ships • 98 – 190 guests
6 Itineraries • 35 Cruises
from $18,980
Signature Collection
Uniworld Boutique River Cruises cruises to South America
Uniworld Boutique River Cruises
River Cruise Line
Small River Ships • 120 – 159 guests
2 Itineraries • 42 Cruises
from $11,949
Signature Collection
Viking Expeditions cruises to South America
Viking Expeditions
Expedition Cruise Line
Small Ships • Up to 378 guests
16 Itineraries • 29 Cruises
from $8,999
Signature Collection
Viking Oceans cruises to South America
Viking Oceans
Upper Premium, Adults Only
Small Ships • Up to 998 guests
3 Itineraries • 17 Cruises
from $7,999
Signature Collection
Virgin Voyages cruises to South America
Virgin Voyages
Contemporary, Adults Only
Large Ships • Up to 2,700 guests
1 Itineraries • 1 Cruises
from $1,854
Signature Collection
Windstar Cruises cruises to South America
Windstar Cruises
Castual Luxury
Very Small to Small • 148 – 342 guests
1 Itineraries • 2 Cruises
from $7,578
Signature Collection

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