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South America Cruises

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South America Cruises

South America cruises encompass a wide range of ocean and river itineraries across an entire continent, with the Amazon Basin representing just one specialized region. Coastal cruises sail along the Atlantic and Pacific shores, connecting major ports such as Buenos Aires, Rio de Janeiro, Valparaíso, and Lima, while also reaching Patagonia, Cape Horn, and the Chilean fjords. Expedition cruising in the Galápagos Islands offers a very different experience focused on wildlife and conservation, while river cruises elsewhere, including Colombia’s Magdalena River, highlight cultural heritage and regional life. Together, South America cruises offer geographic diversity, combining iconic cities, dramatic coastlines, and inland waterways with distinct travel experiences.

South America Cruises Sailing Calendar

Month Number of Itineraries Number of Cruises From Price
Mar 2026 29 36 $123 pp
Apr 2026 6 6 $687 pp
May 2026 2 3 $3,549 pp
Jun 2026 1 1 $3,149 pp
Sep 2026 2 2 $3,299 pp
Oct 2026 3 3 $8,995 pp
Nov 2026 14 15 $95 pp
Dec 2026 30 36 $104 pp
Jan 2027 41 54 $222 pp
Feb 2027 31 45 $811 pp
Mar 2027 27 38 $402 pp
Apr 2027 3 3 $1,433 pp
May 2027 3 5 $3,799 pp
Oct 2027 3 3 $11,995 pp
Nov 2027 3 3 $9,700 pp
Dec 2027 4 4 $1,853 pp
Jan 2028 8 9 $2,859 pp
Feb 2028 5 5 $2,859 pp
Mar 2028 2 2 $3,139 pp

Cruise Lines Sailing to South America

The cruise lines sail to this destination, spanning a variety of cruise line categories and ship sizes. For each cruise line, you’ll find the number of unique itineraries and sailing dates available.  Signature Preferred Partners may offer added value, exclusive perks, or additional savings.

Signature Collection

Cruise Lines with the SC icon are part of the Signature Collection and often include added value, exclusive perks or additional savings. 

AMA Waterways cruises to South America
AMA Waterways
River Cruise Line
Small River Ships • 60 - 165 guests
5 Itineraries • 16 Cruises
from $3,149
Signature Collection
Atlas Ocean Voyages cruises to South America
Atlas Ocean Voyages
Premium / Expedition
Very Small Ships • Up to 200 guests
2 Itineraries • 2 Cruises
from $17,731
Azamara Cruises cruises to South America
Azamara Cruises
Upper Premium
Small Ships • Up to 700 guests
3 Itineraries • 3 Cruises
from $6,589
Signature Collection
Carnival Cruises cruises to South America
Carnival Cruises
Contemporary Cruise Line
Very Large Ships • Up to 5,200 guests
3 Itineraries • 3 Cruises
from $1,314
Signature Collection
Celebrity Cruises cruises to South America
Celebrity Cruises
Premium Cruise Line
Large Ships • Up to 3,200 guests
3 Itineraries • 10 Cruises
from $1,853
Signature Collection
Costa Cruises cruises to South America
Costa Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,500 guests
15 Itineraries • 17 Cruises
from $494
Crystal Cruises cruises to South America
Crystal Cruises
Luxury Cruise Line
Small Ships • Up to 740 guests
1 Itineraries • 1 Cruises
from $9,700
Signature Collection
Explora Journeys cruises to South America
Explora Journeys
Luxury Cruise Line
Small Ships • Up to 920 guests
2 Itineraries • 2 Cruises
from $10,535
Signature Collection
Holland America Line cruises to South America
Holland America Line
Premium Cruise Line
Mid-Size to Large • Up to 2,600 guests
8 Itineraries • 8 Cruises
from $2,159
Signature Collection
MSC Cruises cruises to South America
MSC Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,700 guests
80 Itineraries • 153 Cruises
from $95
Norwegian Cruise Line cruises to South America
Norwegian Cruise Line
Contemporary Cruise Line
Large Ships • Up to 4,000 guests
3 Itineraries • 6 Cruises
from $2,859
Signature Collection
Oceania Cruises cruises to South America
Oceania Cruises
Luxury, Adults Only
Small - Mid-Size • 700 - 1,250 guests
2 Itineraries • 2 Cruises
from $3,649
Signature Collection
Princess Cruises cruises to South America
Princess Cruises
Premium Cruise Line
Mid-Size to Large • up to 4,300 guests
1 Itineraries • 2 Cruises
from $3,297
Signature Collection
Regent Seven Seas Cruises cruises to South America
Regent Seven Seas Cruises
Luxury Cruise Line
Small Ships • 490 – 750 guests
4 Itineraries • 4 Cruises
from $9,849
Signature Collection
Seabourn Cruises cruises to South America
Seabourn Cruises
Luxury & Expedition Cruises
Small Ships • 264 – 600 guests
16 Itineraries • 16 Cruises
from $5,354
Signature Collection
Silversea Cruises cruises to South America
Silversea Cruises
Luxury & Expedition Cruises
Small & Mid-Size • 100 – 728 guests
10 Itineraries • 10 Cruises
from $8,000
Signature Collection
Tauck River Cruises cruises to South America
Tauck River Cruises
River Cruise Line
Small River Ships • 98 – 190 guests
1 Itineraries • 1 Cruises
Please Call
Signature Collection
Viking Expeditions cruises to South America
Viking Expeditions
Expedition Cruise Line
Small Ships • Up to 378 guests
10 Itineraries • 10 Cruises
from $8,995
Signature Collection
Viking Oceans cruises to South America
Viking Oceans
Upper Premium, Adults Only
Small Ships • Up to 998 guests
2 Itineraries • 2 Cruises
from $8,099
Signature Collection
Windstar Cruises cruises to South America
Windstar Cruises
Castual Luxury
Very Small to Small • 148 – 342 guests
2 Itineraries • 5 Cruises
from $7,899
Signature Collection

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