Ohio River cruises carry you through America’s Midwest and Appalachia, showcasing historic cities and verdant landscapes. Enjoy views of rolling hills, charming river towns, and modern skylines. You’ll find local culture, friendly folks, and hearty regional cuisine along the banks. It’s a relaxed journey packed with small-town Americana.
| Month | Number of Itineraries | Number of Cruises | From Price |
|---|---|---|---|
| Apr 2026 | 3 | 5 | Please Call |
| May 2026 | 4 | 16 | Please Call |
| Jun 2026 | 7 | 16 | Please Call |
| Jul 2026 | 6 | 28 | Please Call |
| Aug 2026 | 9 | 24 | Please Call |
| Sep 2026 | 5 | 29 | Please Call |
| Oct 2026 | 5 | 18 | Please Call |
| Jul 2027 | 2 | 14 | Please Call |
| Aug 2027 | 2 | 10 | Please Call |
| Jul 2028 | 2 | 12 | Please Call |
| Aug 2028 | 2 | 12 | Please Call |
| Sep 2028 | 2 | 6 | Please Call |
The cruise lines sailing her span a variety of cruise line categories. For each cruise line, you’ll find the number of unique itineraries and sailing dates available. Signature Preferred Partners may offer added value, exclusive perks, or additional savings.
Cruise Lines with the SC icon are part of the Signature Collection and often include added value, exclusive perks or additional savings.
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