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South America Cruises

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South America Cruises

South America cruises encompass a wide range of ocean and river itineraries across an entire continent, with the Amazon Basin representing just one specialized region. Coastal cruises sail along the Atlantic and Pacific shores, connecting major ports such as Buenos Aires, Rio de Janeiro, Valparaíso, and Lima, while also reaching Patagonia, Cape Horn, and the Chilean fjords. Expedition cruising in the Galápagos Islands offers a very different experience focused on wildlife and conservation, while river cruises elsewhere, including Colombia’s Magdalena River, highlight cultural heritage and regional life. Together, South America cruises offer geographic diversity, combining iconic cities, dramatic coastlines, and inland waterways with distinct travel experiences.

South America Cruises Sailing Calendar

Month Number of Itineraries Number of Cruises From Price
Mar 2026 43 59 $123 pp
Apr 2026 22 39 $133 pp
May 2026 10 30 $3,049 pp
Jun 2026 12 39 $3,149 pp
Jul 2026 13 32 $3,149 pp
Aug 2026 10 31 $3,149 pp
Sep 2026 10 30 $2,999 pp
Oct 2026 24 50 $3,299 pp
Nov 2026 48 83 $99 pp
Dec 2026 60 99 $109 pp
Jan 2027 77 135 $263 pp
Feb 2027 67 104 $811 pp
Mar 2027 81 127 $79 pp
Apr 2027 26 51 $79 pp
May 2027 21 56 $3,299 pp
Jun 2027 16 41 $3,299 pp
Jul 2027 11 28 $7,894 pp
Aug 2027 8 25 $12,599 pp
Sep 2027 10 26 $12,599 pp
Oct 2027 26 55 $4,100 pp
Nov 2027 24 39 $4,100 pp
Dec 2027 14 31 $2,010 pp
Jan 2028 19 21 $2,929 pp
Feb 2028 15 15 $2,479 pp
Mar 2028 5 6 $3,169 pp
Apr 2028 2 2 $11,995 pp
Sep 2028 1 1 $5,094 pp
Nov 2028 1 1 $7,695 pp
Feb 2029 1 1 $22,450 pp

Cruise Lines Sailing to South America

The cruise lines sail to this destination, spanning a variety of cruise line categories and ship sizes. For each cruise line, you’ll find the number of unique itineraries and sailing dates available.  Signature Preferred Partners may offer added value, exclusive perks, or additional savings.

Signature Collection

Cruise Lines with the SC icon are part of the Signature Collection and often include added value, exclusive perks or additional savings. 

AMA Waterways cruises to South America
AMA Waterways
River Cruise Line
Small River Ships • 60 - 165 guests
10 Itineraries • 190 Cruises
from $2,999
Signature Collection
Aqua Expeditions cruises to South America
Aqua Expeditions
Expedition Cruise Line
Very Small Ships • 16 - 40 guests
9 Itineraries • 456 Cruises
Please Call
Signature Collection
Atlas Ocean Voyages cruises to South America
Atlas Ocean Voyages
Premium / Expedition
Very Small Ships • Up to 200 guests
3 Itineraries • 3 Cruises
from $5,094
Aurora Expeditions cruises to South America
Aurora Expeditions
Expedition Cruise Line
Very Small Ships • Up to 150 guests
1 Itineraries • 1 Cruises
Please Call
Avalon Waterways cruises to South America
Avalon Waterways
River Cruise Line
Small River Ships • 36 - 165 guests
6 Itineraries • 42 Cruises
from $7,058
Signature Collection
Azamara Cruises cruises to South America
Azamara Cruises
Upper Premium
Small Ships • Up to 700 guests
11 Itineraries • 11 Cruises
from $2,999
Signature Collection
Carnival Cruises cruises to South America
Carnival Cruises
Contemporary Cruise Line
Very Large Ships • Up to 5,200 guests
3 Itineraries • 3 Cruises
from $1,314
Signature Collection
Celebrity Cruises cruises to South America
Celebrity Cruises
Premium Cruise Line
Large Ships • Up to 3,200 guests
3 Itineraries • 13 Cruises
from $2,010
Signature Collection
Costa Cruises cruises to South America
Costa Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,500 guests
57 Itineraries • 122 Cruises
from $444
Crystal Cruises cruises to South America
Crystal Cruises
Luxury Cruise Line
Small Ships • Up to 740 guests
14 Itineraries • 14 Cruises
from $4,100
Signature Collection
Cunard Line cruises to South America
Cunard Line
Upper Premium
Mid-Size to Large • Up to 3,000 guests
2 Itineraries • 2 Cruises
from $3,399
Signature Collection
Explora Journeys cruises to South America
Explora Journeys
Luxury Cruise Line
Small Ships • Up to 920 guests
5 Itineraries • 5 Cruises
from $8,910
Signature Collection
Holland America Line cruises to South America
Holland America Line
Premium Cruise Line
Mid-Size to Large • Up to 2,600 guests
13 Itineraries • 13 Cruises
from $2,119
Signature Collection
HX Hurtigruten Expeditions cruises to South America
HX Hurtigruten Expeditions
Expedition Cruise Line
Very Small to Small • 90 - 530 guests
1 Itineraries • 1 Cruises
from $6,961
Signature Collection
Lindblad Expeditions cruises to South America
Lindblad Expeditions
Expedition Cruise Line
Very Small Ships • 28 - 120 guests
4 Itineraries • 4 Cruises
from $12,130
Signature Collection
MSC Cruises cruises to South America
MSC Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,700 guests
99 Itineraries • 180 Cruises
from $79
Norwegian Cruise Line cruises to South America
Norwegian Cruise Line
Contemporary Cruise Line
Large Ships • Up to 4,000 guests
3 Itineraries • 6 Cruises
from $2,859
Signature Collection
Oceania Cruises cruises to South America
Oceania Cruises
Luxury, Adults Only
Small - Mid-Size • 700 - 1,250 guests
15 Itineraries • 15 Cruises
from $3,225
Signature Collection
Ponant Cruises cruises to South America
Ponant Cruises
Upper Premium
Very Small to Small • 32 - 264 guests
3 Itineraries • 4 Cruises
from $3,760
Signature Collection
Princess Cruises cruises to South America
Princess Cruises
Premium Cruise Line
Mid-Size to Large • up to 4,300 guests
5 Itineraries • 6 Cruises
from $1,819
Signature Collection
Regent Seven Seas Cruises cruises to South America
Regent Seven Seas Cruises
Luxury Cruise Line
Small Ships • 490 – 750 guests
9 Itineraries • 9 Cruises
from $9,849
Signature Collection
Scenic Cruises cruises to South America
Scenic Cruises
Rivers & Yacht Cruises
Very Small Ships • 68 - 169 guests
17 Itineraries • 18 Cruises
from $6,715
Seabourn Cruises cruises to South America
Seabourn Cruises
Luxury & Expedition Cruises
Small Ships • 264 – 600 guests
23 Itineraries • 24 Cruises
from $6,299
Signature Collection
Silversea Cruises cruises to South America
Silversea Cruises
Luxury & Expedition Cruises
Small & Mid-Size • 100 – 728 guests
15 Itineraries • 15 Cruises
from $8,000
Signature Collection
Swan Hellenic Cruises cruises to South America
Swan Hellenic Cruises
Expedition Cruise Line
Very Small Ships • 152 – 192 guests
5 Itineraries • 5 Cruises
from $4,100
Tauck River Cruises cruises to South America
Tauck River Cruises
River Cruise Line
Small River Ships • 98 – 190 guests
5 Itineraries • 32 Cruises
from $9,290
Signature Collection
Uniworld Boutique River Cruises cruises to South America
Uniworld Boutique River Cruises
River Cruise Line
Small River Ships • 120 – 159 guests
2 Itineraries • 26 Cruises
from $12,149
Signature Collection
Viking Expeditions cruises to South America
Viking Expeditions
Expedition Cruise Line
Small Ships • Up to 378 guests
14 Itineraries • 20 Cruises
from $8,995
Signature Collection
Viking Oceans cruises to South America
Viking Oceans
Upper Premium, Adults Only
Small Ships • Up to 998 guests
3 Itineraries • 12 Cruises
from $8,099
Signature Collection
Windstar Cruises cruises to South America
Windstar Cruises
Castual Luxury
Very Small to Small • 148 – 342 guests
2 Itineraries • 5 Cruises
from $7,899
Signature Collection

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