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South America Cruises

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South America Cruises

South America cruises encompass a wide range of ocean and river itineraries across an entire continent, with the Amazon Basin representing just one specialized region. Coastal cruises sail along the Atlantic and Pacific shores, connecting major ports such as Buenos Aires, Rio de Janeiro, Valparaíso, and Lima, while also reaching Patagonia, Cape Horn, and the Chilean fjords. Expedition cruising in the Galápagos Islands offers a very different experience focused on wildlife and conservation, while river cruises elsewhere, including Colombia’s Magdalena River, highlight cultural heritage and regional life. Together, South America cruises offer geographic diversity, combining iconic cities, dramatic coastlines, and inland waterways with distinct travel experiences.

South America Cruises Sailing Calendar

Month Number of Itineraries Number of Cruises From Price
Jul 2026 8 11 $3,149 pp
Aug 2026 15 48 $3,149 pp
Sep 2026 15 42 $2,999 pp
Oct 2026 23 56 $3,275 pp
Nov 2026 48 99 $83 pp
Dec 2026 75 127 $70 pp
Jan 2027 80 161 $569 pp
Feb 2027 68 125 $559 pp
Mar 2027 89 143 $79 pp
Apr 2027 29 52 $79 pp
May 2027 26 69 $3,299 pp
Jun 2027 21 49 $3,299 pp
Jul 2027 10 27 $7,508 pp
Aug 2027 10 27 $5,694 pp
Sep 2027 19 65 $3,549 pp
Oct 2027 35 73 $3,549 pp
Nov 2027 40 85 $1,248 pp
Dec 2027 28 67 $2,024 pp
Jan 2028 25 32 $3,069 pp
Feb 2028 19 19 $2,439 pp
Mar 2028 17 18 $2,674 pp
Apr 2028 6 6 $5,826 pp
May 2028 2 4 $8,352 pp
Jun 2028 2 2 $8,282 pp
Jul 2028 2 2 $8,282 pp
Aug 2028 3 3 $8,282 pp
Sep 2028 1 1 $31,046 pp
Oct 2028 9 15 $4,450 pp
Nov 2028 11 11 $3,399 pp
Dec 2028 5 5 $4,699 pp
Jan 2029 2 2 $8,999 pp
Feb 2029 5 5 $6,599 pp
Mar 2029 2 3 $9,999 pp
Apr 2029 2 2 $11,999 pp
Oct 2029 3 4 $9,999 pp

Cruise Lines Sailing to South America

The cruise lines sail to this destination, spanning a variety of cruise line categories and ship sizes. For each cruise line, you’ll find the number of unique itineraries and sailing dates available.  Signature Preferred Partners may offer added value, exclusive perks, or additional savings.

Signature Collection

Cruise Lines with the SC icon are part of the Signature Collection and often include added value, exclusive perks or additional savings. 

AMA Waterways cruises to South America
AMA Waterways
River Cruise Line
Small River Ships • 60 - 165 guests
18 Itineraries • 407 Cruises
from $2,999
Signature Collection
Aqua Expeditions cruises to South America
Aqua Expeditions
Expedition Cruise Line
Very Small Ships • 16 - 40 guests
9 Itineraries • 375 Cruises
Please Call
Signature Collection
Atlas Ocean Voyages cruises to South America
Atlas Ocean Voyages
Premium / Expedition
Very Small Ships • Up to 200 guests
2 Itineraries • 2 Cruises
from $17,476
Avalon Waterways cruises to South America
Avalon Waterways
River Cruise Line
Small River Ships • 36 - 165 guests
6 Itineraries • 68 Cruises
from $7,408
Signature Collection
Azamara Cruises cruises to South America
Azamara Cruises
Upper Premium
Small Ships • Up to 700 guests
11 Itineraries • 11 Cruises
from $3,249
Signature Collection
Carnival Cruises cruises to South America
Carnival Cruises
Contemporary Cruise Line
Very Large Ships • Up to 5,200 guests
2 Itineraries • 2 Cruises
from $1,180
Signature Collection
Celebrity Cruises cruises to South America
Celebrity Cruises
Premium Cruise Line
Large Ships • Up to 3,200 guests
3 Itineraries • 12 Cruises
from $2,223
Signature Collection
Costa Cruises cruises to South America
Costa Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,500 guests
47 Itineraries • 114 Cruises
from $361
Crystal Cruises cruises to South America
Crystal Cruises
Luxury Cruise Line
Small Ships • Up to 740 guests
13 Itineraries • 13 Cruises
from $4,100
Signature Collection
Explora Journeys cruises to South America
Explora Journeys
Luxury Cruise Line
Small Ships • Up to 920 guests
5 Itineraries • 5 Cruises
from $9,120
Signature Collection
Holland America Line cruises to South America
Holland America Line
Premium Cruise Line
Mid-Size to Large • Up to 2,600 guests
11 Itineraries • 14 Cruises
from $1,924
Signature Collection
Lindblad Expeditions cruises to South America
Lindblad Expeditions
Expedition Cruise Line
Very Small Ships • 28 - 120 guests
4 Itineraries • 4 Cruises
from $8,491
Signature Collection
MSC Cruises cruises to South America
MSC Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,700 guests
86 Itineraries • 218 Cruises
from $70
Norwegian Cruise Line cruises to South America
Norwegian Cruise Line
Contemporary Cruise Line
Large Ships • Up to 4,000 guests
4 Itineraries • 7 Cruises
from $3,009
Signature Collection
Oceania Cruises cruises to South America
Oceania Cruises
Luxury, Adults Only
Small - Mid-Size • 700 - 1,250 guests
19 Itineraries • 19 Cruises
from $3,399
Signature Collection
Ponant Cruises cruises to South America
Ponant Cruises
Upper Premium
Very Small to Small • 32 - 264 guests
2 Itineraries • 3 Cruises
from $4,600
Signature Collection
Princess Cruises cruises to South America
Princess Cruises
Premium Cruise Line
Mid-Size to Large • up to 4,300 guests
5 Itineraries • 10 Cruises
from $1,972
Signature Collection
Regent Seven Seas Cruises cruises to South America
Regent Seven Seas Cruises
Luxury Cruise Line
Small Ships • 490 – 750 guests
13 Itineraries • 13 Cruises
from $6,599
Signature Collection
Scenic Cruises cruises to South America
Scenic Cruises
Rivers & Yacht Cruises
Very Small Ships • 68 - 169 guests
25 Itineraries • 26 Cruises
from $4,704
Seabourn Cruises cruises to South America
Seabourn Cruises
Luxury & Expedition Cruises
Small Ships • 264 – 600 guests
34 Itineraries • 35 Cruises
from $4,929
Signature Collection
Silversea Cruises cruises to South America
Silversea Cruises
Luxury & Expedition Cruises
Small & Mid-Size • 100 – 728 guests
17 Itineraries • 17 Cruises
from $8,000
Signature Collection
Swan Hellenic Cruises cruises to South America
Swan Hellenic Cruises
Expedition Cruise Line
Very Small Ships • 152 – 192 guests
3 Itineraries • 4 Cruises
from $3,275
Tauck River Cruises cruises to South America
Tauck River Cruises
River Cruise Line
Small River Ships • 98 – 190 guests
5 Itineraries • 15 Cruises
from $9,590
Signature Collection
Uniworld Boutique River Cruises cruises to South America
Uniworld Boutique River Cruises
River Cruise Line
Small River Ships • 120 – 159 guests
2 Itineraries • 14 Cruises
from $13,999
Signature Collection
Viking Expeditions cruises to South America
Viking Expeditions
Expedition Cruise Line
Small Ships • Up to 378 guests
16 Itineraries • 29 Cruises
from $9,299
Signature Collection
Viking Oceans cruises to South America
Viking Oceans
Upper Premium, Adults Only
Small Ships • Up to 998 guests
3 Itineraries • 18 Cruises
from $7,999
Signature Collection
Windstar Cruises cruises to South America
Windstar Cruises
Castual Luxury
Very Small to Small • 148 – 342 guests
2 Itineraries • 5 Cruises
from $7,325
Signature Collection

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