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Cruises from San Diego

Cruises from San Diego give you a laid-back Southern California departure with access to Mexico, the Pacific Coast, and longer repositioning itineraries. Sailing from the downtown waterfront, a cruise from San Diego often features Mexican Riviera routes, Baja California stops, and seasonal sailings. In addition, cruising from San Diego allows you to enjoy the city’s beaches, harbor views, and cultural attractions before or after your voyage, all with convenient air and highway access.

Cruises from San Diego Cruise Calendar

Month	Number of Itineraries	Number of Cruises	From Price
Sep 2026	3	3	$784 pp
Oct 2026	17	19	$249 pp
Nov 2026	16	18	$259 pp
Dec 2026	22	25	$219 pp
Jan 2027	26	36	$288 pp
Feb 2027	15	20	$297 pp
Mar 2027	19	22	$324 pp
Apr 2027	14	18	$362 pp
May 2027	5	5	$559 pp
Aug 2027	2	2	$5,300 pp
Sep 2027	4	4	$888 pp
Oct 2027	17	21	$898 pp
Nov 2027	15	16	$919 pp
Dec 2027	14	14	$769 pp
Jan 2028	9	11	$874 pp
Feb 2028	7	10	$700 pp
Mar 2028	3	8	$748 pp
Apr 2028	11	15	$544 pp
May 2028	1	1	$828 pp
Jun 2028	2	2	$4,500 pp
Dec 2028	1	1	$5,100 pp
Jan 2029	2	2	$14,600 pp

Cruise Lines Sailing from San Diego

The cruise lines who sail from this destination, span a variety of cruise line categories and ship sizes. For each cruise line, you’ll find the number of unique itineraries and sailing dates available. Signature Preferred Partners may offer added value, exclusive perks, or additional savings.