Cruises from Colon

Cruises from Colon

Cruises from Colón give you a strategic Caribbean departure on Panama’s Atlantic coast, closely tied to the Panama Canal. When you choose a cruise from Colón, you can sail on itineraries that transit the Panama Canal or explore the southern Caribbean and Central America. In addition, cruising from Colón allows you to pair your voyage with visits to the Panama Canal, historic forts, and nearby rainforest areas before or after your cruise, making it a practical gateway for canal-focused and regional itineraries.

Cruises from Colon Cruise Calendar

Month Number of Itineraries Number of Cruises From Price
Apr 2026 1 1 $761 pp
May 2026 1 3 $1,190 pp
Jun 2026 1 4 $800 pp
Jul 2026 1 4 $849 pp
Aug 2026 1 5 $894 pp
Sep 2026 2 4 $786 pp
Oct 2026 2 6 $893 pp
Nov 2026 4 4 $1,034 pp
Dec 2026 6 6 $1,009 pp
Jan 2027 13 17 $1,184 pp
Feb 2027 6 8 $955 pp
Mar 2027 4 6 $888 pp
Apr 2027 4 5 $606 pp
Dec 2027 4 7 $899 pp
Jan 2028 6 11 $859 pp
Feb 2028 5 6 $839 pp
Mar 2028 3 4 $919 pp
Apr 2028 4 4 $879 pp

Cruise Lines Sailing from Colon

The cruise lines who sail from this destination, span a variety of cruise line categories and ship sizes. For each cruise line, you’ll find the number of unique itineraries and sailing dates available.  Signature Preferred Partners may offer added value, exclusive perks, or additional savings.

Signature Collection

Cruise Lines with the SC icon are part of the Signature Collection and often include added value, exclusive perks or additional savings. 

Ponant Cruises cruises from Colon (Panama)
Ponant Cruises
Upper Premium
Very Small to Small 32 - 264 guests
9 Itineraries 10 Cruises
from $6,250
Signature Collection
Royal Caribbean Cruises cruises from Colon (Panama)
Royal Caribbean Cruises
Contemporary Cruise Line
Very Large Ships Up to 6,700 guests
18 Itineraries 68 Cruises
from $606
Signature Collection
Sea Cloud Cruises cruises from Colon (Panama)
Sea Cloud Cruises
Specialty / Adventure
Small Sailing Ships 64 – 136 guests
2 Itineraries 2 Cruises
from $7,710
Signature Collection
Windstar Cruises cruises from Colon (Panama)
Windstar Cruises
Castual Luxury
Very Small to Small 148 – 342 guests
7 Itineraries 25 Cruises
from $2,999
Signature Collection

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