Mississippi River cruises transport you along America’s iconic Great River Road. Enjoy Southern hospitality, blues music in Memphis, and Creole flavors in New Orleans. Historic towns and grand plantations provide a glimpse into the country’s past. Sit back, relax, and soak in the heartland charm along this legendary waterway.
| Month | Number of Itineraries | Number of Cruises | From Price |
|---|---|---|---|
| Apr 2026 | 3 | 3 | $6,299 pp |
| May 2026 | 6 | 27 | $6,299 pp |
| Jun 2026 | 12 | 20 | $6,499 pp |
| Jul 2026 | 9 | 15 | $8,999 pp |
| Aug 2026 | 9 | 22 | $5,499 pp |
| Sep 2026 | 8 | 19 | $6,799 pp |
| Oct 2026 | 14 | 24 | $5,799 pp |
| Nov 2026 | 15 | 36 | $4,999 pp |
| Dec 2026 | 10 | 26 | $3,599 pp |
| Jan 2027 | 5 | 10 | $3,799 pp |
| Feb 2027 | 10 | 22 | $4,299 pp |
| Mar 2027 | 12 | 36 | $4,799 pp |
| Apr 2027 | 9 | 36 | $5,999 pp |
| May 2027 | 11 | 35 | $6,299 pp |
| Jun 2027 | 15 | 34 | $6,299 pp |
| Jul 2027 | 9 | 17 | $6,999 pp |
| Aug 2027 | 6 | 20 | $6,499 pp |
| Sep 2027 | 7 | 23 | $6,499 pp |
| Oct 2027 | 14 | 25 | $6,499 pp |
| Nov 2027 | 13 | 36 | $4,999 pp |
| Dec 2027 | 11 | 29 | $3,799 pp |
| Jan 2028 | 3 | 4 | $4,499 pp |
| Feb 2028 | 11 | 29 | $4,499 pp |
| Mar 2028 | 12 | 43 | $4,999 pp |
| Apr 2028 | 12 | 48 | $5,999 pp |
| May 2028 | 8 | 45 | $6,299 pp |
| Jun 2028 | 10 | 27 | $6,499 pp |
| Jul 2028 | 10 | 26 | $6,999 pp |
| Aug 2028 | 7 | 25 | $6,999 pp |
| Sep 2028 | 9 | 31 | $6,799 pp |
| Oct 2028 | 13 | 28 | $6,499 pp |
| Nov 2028 | 9 | 35 | $4,999 pp |
| Dec 2028 | 9 | 31 | $3,999 pp |
The cruise lines sailing her span a variety of cruise line categories. For each cruise line, you’ll find the number of unique itineraries and sailing dates available. Signature Preferred Partners may offer added value, exclusive perks, or additional savings.
Cruise Lines with the SC icon are part of the Signature Collection and often include added value, exclusive perks or additional savings.
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