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South America Cruises

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South America Cruises

South America cruises encompass a wide range of ocean and river itineraries across an entire continent, with the Amazon Basin representing just one specialized region. Coastal cruises sail along the Atlantic and Pacific shores, connecting major ports such as Buenos Aires, Rio de Janeiro, Valparaíso, and Lima, while also reaching Patagonia, Cape Horn, and the Chilean fjords. Expedition cruising in the Galápagos Islands offers a very different experience focused on wildlife and conservation, while river cruises elsewhere, including Colombia’s Magdalena River, highlight cultural heritage and regional life. Together, South America cruises offer geographic diversity, combining iconic cities, dramatic coastlines, and inland waterways with distinct travel experiences.

South America Cruises Sailing Calendar

Month Number of Itineraries Number of Cruises From Price
Sep 2026 5 5 $4,049 pp
Oct 2026 4 4 $8,995 pp
Nov 2026 14 14 $525 pp
Dec 2026 39 48 $393 pp
Jan 2027 50 57 $559 pp
Feb 2027 45 52 $559 pp
Mar 2027 31 34 $423 pp
Apr 2027 6 6 $119 pp
May 2027 5 6 $3,549 pp
Jun 2027 2 2 $14,804 pp
Oct 2027 4 4 $6,509 pp
Nov 2027 1 1 $1,258 pp
Dec 2027 7 7 $2,124 pp
Jan 2028 13 14 $3,069 pp
Feb 2028 5 5 $2,654 pp
Mar 2028 8 8 $3,389 pp
Aug 2028 1 1 $48,596 pp
Sep 2028 1 1 $31,047 pp
Oct 2028 5 5 $4,225 pp
Feb 2029 1 1 $13,499 pp
Oct 2029 2 2 $10,999 pp

Cruise Lines Sailing to South America

The cruise lines sail to this destination, spanning a variety of cruise line categories and ship sizes. For each cruise line, you’ll find the number of unique itineraries and sailing dates available.  Signature Preferred Partners may offer added value, exclusive perks, or additional savings.

Signature Collection

Cruise Lines with the SC icon are part of the Signature Collection and often include added value, exclusive perks or additional savings. 

AMA Waterways cruises to South America
AMA Waterways
River Cruise Line
Small River Ships • 60 - 165 guests
18 Itineraries • 28 Cruises
from $3,249
Signature Collection
Atlas Ocean Voyages cruises to South America
Atlas Ocean Voyages
Premium / Expedition
Very Small Ships • Up to 200 guests
2 Itineraries • 2 Cruises
from $17,731
Azamara Cruises cruises to South America
Azamara Cruises
Upper Premium
Small Ships • Up to 700 guests
4 Itineraries • 4 Cruises
from $4,989
Signature Collection
Carnival Cruises cruises to South America
Carnival Cruises
Contemporary Cruise Line
Very Large Ships • Up to 5,200 guests
2 Itineraries • 2 Cruises
from $1,321
Signature Collection
Celebrity Cruises cruises to South America
Celebrity Cruises
Premium Cruise Line
Large Ships • Up to 3,200 guests
3 Itineraries • 10 Cruises
from $1,946
Signature Collection
Costa Cruises cruises to South America
Costa Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,500 guests
9 Itineraries • 9 Cruises
from $415
Explora Journeys cruises to South America
Explora Journeys
Luxury Cruise Line
Small Ships • Up to 920 guests
2 Itineraries • 2 Cruises
from $9,595
Signature Collection
Holland America Line cruises to South America
Holland America Line
Premium Cruise Line
Mid-Size to Large • Up to 2,600 guests
8 Itineraries • 10 Cruises
from $2,124
Signature Collection
MSC Cruises cruises to South America
MSC Cruises
Contemporary Cruise Line
Very Large Ships • Up to 6,700 guests
98 Itineraries • 141 Cruises
from $119
Norwegian Cruise Line cruises to South America
Norwegian Cruise Line
Contemporary Cruise Line
Large Ships • Up to 4,000 guests
4 Itineraries • 7 Cruises
from $3,009
Signature Collection
Oceania Cruises cruises to South America
Oceania Cruises
Luxury, Adults Only
Small - Mid-Size • 700 - 1,250 guests
1 Itineraries • 1 Cruises
from $4,549
Signature Collection
Princess Cruises cruises to South America
Princess Cruises
Premium Cruise Line
Mid-Size to Large • up to 4,300 guests
5 Itineraries • 8 Cruises
from $1,772
Signature Collection
Regent Seven Seas Cruises cruises to South America
Regent Seven Seas Cruises
Luxury Cruise Line
Small Ships • 490 – 750 guests
2 Itineraries • 2 Cruises
from $13,499
Signature Collection
Scenic Cruises cruises to South America
Scenic Cruises
Rivers & Yacht Cruises
Very Small Ships • 68 - 169 guests
1 Itineraries • 1 Cruises
from $16,345
Seabourn Cruises cruises to South America
Seabourn Cruises
Luxury & Expedition Cruises
Small Ships • 264 – 600 guests
25 Itineraries • 26 Cruises
from $6,298
Signature Collection
Silversea Cruises cruises to South America
Silversea Cruises
Luxury & Expedition Cruises
Small & Mid-Size • 100 – 728 guests
2 Itineraries • 2 Cruises
from $23,300
Signature Collection
Swan Hellenic Cruises cruises to South America
Swan Hellenic Cruises
Expedition Cruise Line
Very Small Ships • 152 – 192 guests
1 Itineraries • 1 Cruises
from $4,225
Uniworld Boutique River Cruises cruises to South America
Uniworld Boutique River Cruises
River Cruise Line
Small River Ships • 120 – 159 guests
2 Itineraries • 2 Cruises
from $14,804
Signature Collection
Viking Expeditions cruises to South America
Viking Expeditions
Expedition Cruise Line
Small Ships • Up to 378 guests
7 Itineraries • 8 Cruises
from $6,495
Signature Collection
Viking Oceans cruises to South America
Viking Oceans
Upper Premium, Adults Only
Small Ships • Up to 998 guests
2 Itineraries • 6 Cruises
from $7,999
Signature Collection
Windstar Cruises cruises to South America
Windstar Cruises
Castual Luxury
Very Small to Small • 148 – 342 guests
2 Itineraries • 5 Cruises
from $7,010
Signature Collection

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