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Cruises from San Diego

Cruises from San Diego give you a laid-back Southern California departure with access to Mexico, the Pacific Coast, and longer repositioning itineraries. Sailing from the downtown waterfront, a cruise from San Diego often features Mexican Riviera routes, Baja California stops, and seasonal sailings. In addition, cruising from San Diego allows you to enjoy the city’s beaches, harbor views, and cultural attractions before or after your voyage, all with convenient air and highway access.

Cruises from San Diego Cruise Calendar

Month	Number of Itineraries	Number of Cruises	From Price
May 2026	2	2	$219 pp
Aug 2026	2	2	$5,135 pp
Sep 2026	2	2	$784 pp
Oct 2026	13	14	$329 pp
Nov 2026	9	10	$399 pp
Dec 2026	16	17	$339 pp
Jan 2027	17	21	$336 pp
Feb 2027	9	10	$347 pp
Mar 2027	4	4	$749 pp
Apr 2027	6	6	$464 pp
May 2027	2	2	$616 pp
Aug 2027	1	1	$10,670 pp
Oct 2027	6	6	$964 pp
Nov 2027	5	5	$1,069 pp
Dec 2027	7	7	$769 pp
Jan 2028	1	1	$3,174 pp
Feb 2028	1	1	$4,524 pp
Apr 2028	4	4	$544 pp

Cruise Lines Sailing from San Diego

The cruise lines who sail from this destination, span a variety of cruise line categories and ship sizes. For each cruise line, you’ll find the number of unique itineraries and sailing dates available. Signature Preferred Partners may offer added value, exclusive perks, or additional savings.